陈向峰，男，浙江金华人，2019年博士毕业于浙江大学动物科学学院动物科学系，同年进入浙江大学医学院脑科学与脑医学系进行博士后工作，2022年博士后出站并加入浙江工商大学食品与生物工程学院，主要研究方向为益生菌及其代谢产物的功能和机制，以及植物源食品生物活性物质的分离纯化和功能分析。

主持或参加科研项目（课题）

1. 中国博士后科学基金会，第67批面上资助面上项目，从免疫负调节角度比较分析植物多糖和脂多糖活化巨噬细胞的不同作用机制，2020-07至2022-06，8万元，已结题，主持。

2. 青年项目, 31802107, 畜禽污水中游离耐药基因超声波辅助酶解效果与机理研究,2019-01至2021-12, 20万元, 已结题, 参加。

3. 国家自然科学基金委员会, 面上项目, 31472229, 基于诱导宿主细胞释放 DNA 的皂苷佐剂作用机制研究,2015-01至2018-12, 86万元, 已结题, 参加。

4. 国家自然科学基金委员会, 面上项目, 31272597, 白藤梨多糖佐剂作用新的细胞和分子机制研究,2013-01至2016-12, 80万元, 已结题, 参加。

5. 浙江省自然科学基金重点项目，LZ13C180001，皂苷佐剂对局部组织先天性免疫微环境的调控作用研究，2013-01至2016-12，30 万元，已结题，参加。

6. 引进国际先进农业科学技术计划（948 计划）项目，2013-S17，兽用疫苗佐剂新技术引进与新型佐剂开发，2013-01至2014-12，50 万元，已结题，参加。

代表性论著

1. Han Ziyi^#, Jin Junjie^#, Chen Xiangfeng, He Yanfei, Sun Hongxiang^*. Adjuvant activity of tubeimosides by mediating the local immune microenvironment. Frontiers in Immunology. 2023,14.

2. Jin Shuang^#, Chen Xiangfeng^#, Zheng Hanyu^#, Cai Wanxiong^#, Lin Xurong^#, Kong Xiangxing, Ni Yingchun, Ye Jingjia, Li Xiaodan, Shen Luoan, Guo Binjie, Abdelrahman Zeinab, Zhou Songlin, Mao Susu, Wang Yaxian, Yao Chun, Gu Xiaosong, Yu Bin, Wang Zhiping^*, Wang Xuhua^*. Downregulation of UBE4B promotes CNS axon regrowth and functional recovery after stroke. iScience. 2022, 26(1):105885.

3. He Yanfei, Hu Xiaoying, Zhang Huifang, Chen Xiangfeng, Sun Hongxiang^*. Adjuvant effect of two polysaccharides from the petals of Crocus sativus and its mechanisms. International Journal of Biological Macromolecules, 2022, 204: 50-61.

4. Lin Lingmin, He Zewei, Zhang Tianfang, Zuo Yanmin, Chen Xiangfeng, Abdelrahman, Zeinab, Chen Feihong, Wei Zhongchao, Si Ke, Gong Wei, Wang Xuhua, He Sailing, Chen Zuobin^*. A biocompatible two-photon absorbing fluorescent mitochondrial probe for deep in vivo bioimaging. J Mater Chem B. 2022, 10(6): 887-898.

5. Chen Xiangfeng, He Yanfei, Zhu Yongliang, Du Jing, Sun Hongxiang^*. linc-AAM facilitates gene expression contributing to macrophage activation and adaptive immune responses. Cell Reports. 2021,34.

6. Ye Jingjia^#，Jin Shuang^#, Cai Wanxiong^#, Chen Xiangfeng^#, Zheng Hanyu, Zhang Tianfang, Lu Wujie, Li Xiaojian, Liang Chengzhen, Chen Qixin，Wang Yaxin，Gu Xiaosong, Yu Bin, Chen Zuobin^*，Wang Xuhua^*. Rationally Designed, Self-Assembling, Multifunctional Hydrogel Depot Repairs Severe Spinal Cord Injury，ADVANCED HEALTHCARE MATERIALS, 2021, 10(13):2100242. DOI:10.1002/adhm.202100242.

7. Chen Xiangfeng^#, Du Jing^#, Zhu Yongliang, Zhang Caiqiao, Sun Hongxiang^*. Comprehensive analysis of lncRNA and mRNA expression profiles in macrophages activated by Actinidia eriantha polysaccharide. Int Immunopharmacol. 2019,136:980-993.

8. Chen Xiangfeng^#, Yuan Lijia^#, Du Jing, Zhang Caiqiao, Sun Hongxiang^*.The polysaccharide from the roots of Actinidia eriantha activates RAW264.7 macrophages via regulating microRNA expression. Int Immunopharmacol. 2019, 132: 203–212.

9. Wang Chenying, Du Jing, Chen Xiangfeng, Zhu Yongliang, Sun Hongxiang^*. Activation of RAW264.7 macrophages by active fraction of Albizia julibrissin saponin via Ca2+–ERK1/2–CREB–lncRNA pathways. Int Immunopharmacol. 2019, 77.

10. Du Jing, Chen Xiangfeng, Ye yiping, Sun Hongxiang^*. Distinct mechanisms of innate immune responses in mice induced by Alum and Actinidia eriantha polysaccharide. Int Immunopharmacol.. 2019,19: 34782-34788.

11. Du Jing^#, Chen Xiangfeng^#, Wang Chenying, Sun Hongxiang^*. Pathway analysis of global gene expression change in dendritic cells induced by the polysaccharide from the roots of Actinidia eriantha. J Ethnopharmacol. 2018, 214: 141–152.

12. Sodrul Islam MD, Wang Chenying, Chen Xiangfeng, Du Jing, Sun Hongxiang^*. Role of ginsenosides in reactive oxygen species-mediated anticancer therapy. Oncotarget. 2017 9(2): 2931-2950.

13. Sun Hongxiang^*, Zhang Juan, Chen Fengyang, Chen Xiangfeng, Zhou Zhihua, Wang Hui. Activation of RAW264.7 macrophages by the polysaccharide from the roots of Actinidia eriantha and its molecular mechanisms. Carbohydr Polym. 2015;121:388-402.

14. Wang Juanjuan, Han Hua, Chen Xiangfeng, Yi Yanghua, Sun Hongxiang^*. Cytotoxic and apoptosis-inducing activity of triterpene glycosides from Holothuria scabra and Cucumaria frondosa against HepG2 cells. Mar Drugs. 2014, 12(8):4274-90. doi: 10.3390/md12084274.

15. Wang Juanjuan, Chen Xiangfeng, Zhou Zhihua, Li Jinhui, Sun Hongxiang^*. The Inhibitory Effect of 3 β-Hydroxy-12-oleanen-27-oic Acid on Growth and Motility of Human Hepatoma HepG2 Cells through JNK and Akt Signaling Pathway. Evid Based Complement Alternat Med. 2013: 685159.