郦萍,女,1981年2月生,研究员,博士生导师,浙江诸暨人。2009年获浙江大学微生物学博士学位,2009-2014年在美国Florida State University从事5年博士后研究工作,现为浙江工商大学食品与生物工程学院副院长、食品微生物研究所副所长。
入选教育部重要人才计划青年学者、浙江省杰出青年基金项目、浙江省高层次人才特殊支持计划青年拔尖人才、第六届中国国际“互联网+”大学生创新创业大赛优秀导师,为中国食品学会益生菌分会第三届理事会理事、浙江省奶业协会乳品加工委员会副主任、浙江省生物信息学学会微生物专业委员会委员,是国家创新人才推进计划重点领域创新团队核心骨干成员。现担任Adv Gut Microbio Res等多个国际期刊编委,Front Cell
Infect Mi特刊客座编辑,及Crit Rev Food Sci、Engineering等10余个权威期刊审稿人,国家自然科学基金等项目通讯评审专家。
主持国家自然科学基金(3项)、国家重点研发计划(子课题)、浙江省重点研发计划、省基金等项目,作为主要完成人参与国家及省部级项目10余项、美国NSF项目2项;在Cell子刊Cell Stem Cell、J Cell Biol、J Agric Food Chem、Food Chem等期刊发表论文70余篇,参编英文专著3部。研究成果获国家科技进步奖二等奖1项(5/10)、浙江省科技进步奖一等奖1项(3/12);并以第一完成人获中国食品学会科技创新奖优秀论文二等奖,入围“2022年度中国食品科技十大进展”评选。指导学生荣获第六届中国国际“互联网+”大学生创新创业大赛国赛金奖、省赛金奖和金钥匙奖。
主要研究方向:
1. 抗菌肽资源挖掘及其抑菌机理研究
2. 益生菌活性成分(抗菌肽、B族维生素、外泌体等)对肠道微生态的调控分子机制
3. 特色益生菌菌种库构建、产品研发及产业化关键技术
4. 益生菌、益生元、后生元与机体健康
部分代表性论著:
[1] The Zika Virus Capsid Disrupts Corticogenesis by Suppressing Dicer Activity and miRNA Biogenesis. Cell Stem Cell. 2020, 27(4):618-632.
[2] Ndj1, a telomere-associated protein, regulates centrosome separation in budding yeast meiosis. J Cell Biol. 2015, 209(2):247-59.
[3] Lactobacillus plantarum ZJ316 improves the quality of Stachys sieboldii Miq. pickle by inhibiting harmful bacteria growth and degrading nitrite, promoting the gut microbiota health in vitro. Food Funct. 2022, 13(3):1551-1562.
[4] Use of Lactiplantibacillus plantarum ZJ316 as a starter culture for nitrite degradation, foodborne pathogens inhibition and microbial community modulation in pickled mustard fermentation, Food Chemistry-X. 2022, 14:100344.
[5] Lactobacillus plantarum ZJ316 Attenuates Helicobacter pylori-Induced Gastritis in C57BL/6 Mice. J Agric Food Chem. 2021, 69(23):6510-6523.
[6] Phenyl lactic acid alleviates Samonella Typhimurium-induced colitis via regulating microbiota composition, SCFA production and inflammatory responses. Food Funct. 2021, 12(12):5591-5606.
[7] Cleavage of the SUN-domain protein Mps3 at its N-terminus regulates centrosome disjunction in budding yeast meiosis. PLoS Genet. 2017, 13(6):e1006830.
[8] Characterization of extracellular vitamin B12 producing Lactobacillus plantarum strains and assessment of the probiotic potentials. Food Chem. 2017, 234:494-501.
[9] Purification, characterization, and mode of action of Paracin 54, a novel bacteriocin against Staphylococci. Appl Microbiol Biotechnol. 2021 ,105(18):6735-6748.
[10] Anti-Salmonella mode of action of natural L-phenyl lactic acid purified from Lactobacillus plantarum ZJ316. Appl Microbiol Biotechnol. 2020, 104(12):5283-529
[11] Purification and characterization of a novel bacteriocin from Lactobacillus paracasei ZFM54. LWT- Food Sci Technol, 2021, 143(1):111125.
[12] lantaricin NC8 from Lactobacillus plantarum causes cell membrane disruption to Micrococcus luteus without targeting lipid II. Appl Microbiol Biotechnol. 2018,102(17):7465-7473.
[13] Novel vitamin B12-producing Enterococcus spp. and preliminary in vitro evaluation of probiotic potentials. Appl Microbiol Biotechnol. 2017, 101(15):6155-6164.
[14] Condensin suppresses recombination and regulates double-strand break processing at the repetitive rDNA array to ensure proper chromosome segregation during meiosis in budding yeast, Mol Biol Cell. 2014, 25(19):2934-47.
[15] Probiotics-Current Knowledge and Future Prospects, Chapter 1, In book: Antimicrobial effects of probiotics and novel probiotic based approaches for infectious diseases, 2018. ISBN 978-953-51-5911-7.
联系方式:
浙江工商大学食品与生物工程学院
联系地址:中国杭州(310018)钱塘新区学正街18号
Email: ping-biology@outlook.com
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