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周涛教授,博士生导师
( 发布日期:2019/2/21 阅读:次)

   周涛,男,1966年9月出生,浙江舟山人,博士,教授,博士生导师。1986年毕业于浙江师范大学,于2001年获浙江大学理博士学位。2002年1月 至2008年4月在英国伦敦大学国王学院药学系进行博士后研究工作,现为该校药物科学研究所访问高级研究员。2014年12月 至2015年5月在美国佐治亚大学食品科学与技术系进行访问研究。2008年5月起任职于浙江工商大学食品与生物工程学院。

   目前承担无机及分析化学、有机合成化学与路线设计策略、食品中的化学方法、功能性食品学等课程的教学任务。主要从事食品科学及药物化学方面的研究,先后承接国家自然科学基金、教育部留学回国人员启动基金、浙江省科技厅项目2项、浙江省自然科学基金2项及厅市级项目多项,参与国家和省部级重点研发项目多项。主持完成的浙江省教育厅项目(鲐鱼功能食品开发研究)获省高校科研成果三等奖。在国际著名杂志Journal of Medicinal Chemistry, Chemical Communications, Journal of Agricultural and Food Chemistry, Food Chemistry, Food control, Food and Bioprocess Technology, Dalton Transaction,European Journal of Medicinal Chemistry, International Journal of Biological Macromolecules 等国内外学术期刊上发表论文100多篇,其中70多篇被SCI收录。获授权国家发明专利15件。

  

主要研究方向:

天然活性多糖的结构、功能研究;功能性食品研究;水产品保鲜及机理研究;药物化学


联系方式:

Email:taozhou@zjgsu.edu.cn


近几年代表性论文:

1. Mei-Jia Shi, Fan Wang, Hui Jiang, Wen-Wen Qian, Yuan-Yuan Xie, Xiao-Yi Wei, Tao Zhou*. Effect of enzymatic degraded polysaccharides from Enteromorpha prolifera on the physical and oxidative stability of fish oil-in-water emulsions. Food Chem. 2020, 322, 126774.

2. Yin-Ting Li, Yun-Feng Huo, Fan Wang, Chong Wang, Qing Zhu, Yan-Bo Wang, Ling-Lin Fu,* Tao Zhou*. Improved antioxidant and immunomodulatory activities of enzymatically degraded Porphyra haitanensis polysaccharides. J. Food Biochem. 2020, e13189.

3. Tao Zhou,* Xiao-Le Kong,  and Robert C Hider*. Synthesis and iron chelating properties of hydroxypyridinone and hydroxypyranone hexadentate ligands. Dalton Trans. 2019, 48, 3459–3466.

4. Le-Le Shao, Jia-Min Zhou, Qing Zhu, Xiao-Ling Wang, Robert C Hider, Tao Zhou*. Enzymatic characteristics of polyphenoloxidase from shrimp (Penaeus vannamei) and its inhibition by a novel hydroxypyridinone derivative. Food Sci. Biotechnol. 2019, 28, 1047-1055.

5. Si-Qi Yang, Xiao-Yan Dai, Xiao-Yi Wei, Qing Zhu, Tao Zhou*. Co-immobilization of pectinase and glucoamylase onto sodium aliginate/graphene oxide composite beads and its application in the preparation of pumpkin-hawthorn juice. J. Food Biochem. 2019, 43:e12741.

6. Kai Chen, Le-Le Shao, Yun-Feng Huo, Jia-Min Zhou, Qing Zhu, Robert C Hider, Tao Zhou*. Antimicrobial and antioxidant effects of a hydroxypyridinone derivative containing an oxime ether moiety and its application in shrimp preservation. Food Control 2019, 95, 157-164.

7. Tao Zhou*, Sinan Battah, Francesca Mazzacuva, Robert C. Hider, Paul Dobbin, Alexander J. MacRobert. Design of Bifunctional Dendritic 5-Aminolevulinic Acid and Hydroxypyridinone Conjugates for Photodynamic Therapy. Bioconjugate Chem. 2018, 29, 3411–3428.

8. Yin-Ting Li, Bing-Jie Chen, Wei-Du Wu, Kun Ge, Xiao-Yi Wei, Li-Min Kong, Yuan-Yuan Xie, Jin-Ping Gu, Jin-Chao Zhang, Tao Zhou*. Antioxidant and antimicrobial evaluation of carboxylmethylated and hydroxamated degraded polysaccharides from Sargassum fusiforme. Int. J. Biol. Macromol. 2018, 118, 1550-1557.

9. Tao Zhou*, Kai Chen, Li-Min Kong, Mu-Song Liu, Yong-Min Ma, Yuan-Yuan Xie, Robert C. Hider*. Synthesis, iron binding and antimicrobial properties of hexadentate 3-hydroxypyridinones-terminated dendrimers. Bioorg. Med. Chem. Lett. 2018, 28, 2504-2512.

10. Xiao-Yan Dai, Li-Min Kong, Xiao-Lin Wang, Qing Zhu, Kai Chen, Tao Zhou*. Preparation, characterization and catalytic behavior of pectinase covalently immobilized onto sodium alginate/graphene oxide composite beads. Food Chem. 2018, 253, 185-193.

11. Le-Le Shao, Xiao-Ling Wang, Kai Chen, Xiao-Wu Dong, Li-Min Kong, De-Yin Zhao, Robert C Hider, Tao Zhou*. Novel hydroxypyridinone derivatives containing an oxime ether moiety: synthesis, inhibition on mushroom tyrosinase and application in anti-browning of fresh-cut apples. Food Chem. 2018, 242, 174-181.

12. Kai Chen, De-Yin Zhao, Yu-Lin Chen, Xiao-Yi Wei, Yin-Ting Li, Li-Min Kong, Robert C Hider, Tao Zhou*. A novel inhibitor against mushroom tyrosinase with a double action mode and its application in controlling the browning of potato. Food Bioprocess Technol. 2017, 10, 2146-2155.

13. Le-Le Shao, Jie Xu, Mei-Jia Shi, Xiao-Ling Wang, Yin-Ting Li, Li-Min Kong, Robert C Hider, Tao Zhou*. Preparation, Antioxidant and Antimicrobial Evaluation of Hydroxamated Degraded Polysaccharides from Enteromorpha prolifera. Food Chem. 2017, 237, 481-487.

14. Sinan Battah, Robert C. Hider, Alexander J. MacRobert, Paul S. Dobbin, Tao Zhou*. Hydroxypyridinone and 5-Aminolaevulinic Acid Conjugates for Photodynamic Therapy. J. Med. Chem. 2017, 60, 3498−3510.

15. Hao-Chen Ding, Dong-Fang Li, Xiao-Yi Wei, Yao-Wen Huang, Shuai Cui, Hu-Jun Xie, Tao Zhou*. Protein-peptide nutritional material prepared from surimi wash-water using immobilized chymotrypsin-trypsin. J. Sci. Food Agri. 2017, 97, 1746-1752.

16. Mei-Jia Shi, Xiaoyi Wei, Jie Xu, Bing-Jie Chen, De-Yin Zhao, Shuai Cui, Tao Zhou*. Carboxymethylated Degraded Polysaccharides from Enteromorpha prolifera: Preparation and in Vitro Antioxidant Activity. Food Chem. 2017, 215, 76–83.

17. Bing-Jie Chen, Mei-Jia Shi, Shuai Cui, Shu-Xian Hao, Robert C Hider, Tao Zhou*. Improved antioxidant and anti-tyrosinase activity of polysaccharide from Sargassum fusiforme by degradation. Int. J. Biol. Macromol. 2016, 92, 715–722.

18. De-Yin Zhao, Ming-Xia Zhang, Xiaowu Dong, Yong-Zhou Hu, Xiao-Yan Dai, Xiaoyi Wei, Robert C Hider, Jin-Chao Zhang, Tao Zhou*. Design and synthesis of novel hydroxypyridinone derivatives as potential tyrosinase inhibitors. Bioorg. Med. Chem. Lett. 2016, 26, 3103-3108.

19. Xiao-Yan Dai, Ming-Xia Zhang, Xiao-Yi Wei, Robert C Hider, Tao Zhou*, Novel Multifunctional Hydroxypyridinone Derivatives as Potential Shrimp Preservatives. Food Bioprocess Technol. 2016, 9, 1079-1088.

20. Bing-Jie Chen,Ying-Jun Zhou,Xiao-Yi Wei,Hu-Jun Xie,Robert C. Hider,Tao Zhou*. Edible Antimicrobial Coating Incorporating a Polymeric Iron Chelator and Its Application in the Preservation of Surimi Product. Food Bioprocess Technol. 2016, 9, 1031-1039.

21. Qin-Wei Zhou, Hao-Chen Ding, Dong-Fang Li, Yan-Ping Zhang, Zhi-Yuan Dai, Tao Zhou*. Antioxidant activity of enzymatic hydrolysate derived from hairtail surimi wash water using an immobilized chymotrypsin–trypsin column reactor. J. Food Biochem. 2016, 40, 39-46.

22. Jie Xu, Li-Li Xu, Qin-Wei Zhou, Shu-Xian Hao, Tao Zhou*, Hu-Jun Xie. Isolation, Purification, and Antioxidant Activities of Degraded Polysaccharides from Enteromorpha prolifera. Int. J. Biol. Macromol. 2015, 81, 1026-1030.

23. Ying-Jun Zhou, Mu-Song Liu, Al Rugaie Osamah, Xiao-Le Kong, Selwa Alsam, Sinan Battah, Yuan-Yuan Xie, Robert C. Hider, Tao Zhou*. Hexadentate 3-hydroxypyridin-4-ones with high iron(III) affinity: design, synthesis and inhibition on methicillin resistant Staphylococcus aureus and Pseudomonas strains. Euro. J. Med. Chem. 2015, 94, 8-21.

24. Ying-Jun Zhou, Xiao-Le Kong, Jun-Pei Li, Yong-Min Ma, Robert C Hider and Tao Zhou*. Novel 3-hydroxypyridin-4-one hexadentate ligand-based polymeric iron chelator: synthesis, characterization and antimicrobial evaluation. MedChemComm 2015, 6, 1620-1625.

25. Tao Zhou, Robert C. Hider, Xiaole Kong*. Mode of iron(III) chelation by hexadentate hydroxypyridinones. Chem. Commun. 2015, 51, 5614-5617.

26. Ying-Jun Zhou, Ming-Xia Zhang, Robert C. Hider, Tao Zhou*. In vitro antimicrobial activity of hydroxypyridinone hexadentate-based dendrimeric chelators alone and in combination with norfloxacin. FEMS Microbiol. Lett. 2014, 355, 124-130.

27. Ming-Xia Zhang, Chun-Feng Zhu, Ying-Jun Zhou, Xiao-Le Kong, Robert C Hider, Tao Zhou*. Design, synthesis and antimicrobial evaluation of hexadentate hydroxypyridinones with high iron(III) affinity. Chem. Biol. Drug Des. 2014, 84, 659–668.

28. Li-Li Xu, Pan-Pan Hu, Xiao-Le Kong, Robert C Hider, Tao Zhou*, Zhi-Yuan Dai. 3-Hydroxypyridinone-L-phenylalanine conjugates with antimicrobial and tyrosinase inhibitory activities as potential shrimp preservatives. Int. J. Food Sci. Technol. 2014, 49, 797–803.

29. Dong-Fang Li, Hao-Chen Ding, and Tao Zhou*. Covalent Immobilization of Mixed Proteases, Trypsin and Chymotrypsin, onto Modified Polyvinyl Chloride Microspheres. J. Agri. Food Chem. 2013, 61, 10447−10453.

30. Dong-Fang Li, Pan-Pan Hu, Mu-Song Liu, Xiao-Le Kong, Jin-Chao Zhang, Robert C Hider, Tao Zhou*. Design and synthesis of hydroxypyridinone-L-phenylalanine conjugates as potential tyrosinase inhibitors. J. Agri. Food Chem. 2013, 61, 6597-6603.


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